Letter by Williams and Tabas Regarding Article “Atherosclerosis 2005: Recent Discoveries and Novel Hypotheses”

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Atherosclerosis 2005: recent discoveries and novel hypotheses.

“Atherosclerosis 2005: Recent Discoveries and Novel Hypotheses” We thank Drs Williams and Tabas for their interest in our work1 and agree that there is a substantial body of evidence supporting the role of hyperlipidemia in atherogenesis. In our review, we addressed this point and indicated that cholesterol may be sufficient to alter the homeostasis of the arterial wall in susceptible individua...

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Recent Discoveries and Novel Hypotheses

Atherosclerosis is an inflammatory process that selectively affects arteries and is highly prevalent in both women and men. Thrombo-occlusive complications of atherosclerosis, including stroke and myocardial infarction, are major causes of morbidity and mortality. Senescence of the arterial tree is a biological process that follows a natural course that can be accelerated by the combined injury...

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ژورنال

عنوان ژورنال: Circulation

سال: 2006

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.105.606962